Publications related to APEX technology

Fluoride-Cleavable, Fluorescently Labelled Reversible Terminators: Synthesis and Use in Primer Extension.

Knapp DC, Serva S, D'Onofrio J, Keller A, Lubys A, Kurg A, Remm M, Engels JW.

Chemistry. 2011 Feb 3. doi: 10.1002/chem.201001952.

Molecular diagnosis of Down syndrome using quantitative APEX-2 microarrays.

Oitmaa E, Peters M, Vaidla K, Andreson R, Mägi R, Slavin G, Velthut A, Tõnisson N, Reimand T, Remm M, Schneider M, Ounap K, Salumets A, Metspalu A.

Prenat Diagn. 2010 Dec;30(12-13):1170-7.

ThalassoChip, an array mutation and single nucleotide polymorphism detection tool for the diagnosis of beta-thalassaemia.

Shammas C, Papasavva T, Felekis X, Christophorou C, Roomere H, Synodinos JT, Kanavakis E, El-Khateeb M, Hamamy H, Mahmoud T, Shboul M, El Beshlawy A, Filon D, Hussein IR, Galanello R, Romeo G, Kleanthous M.

Clin Chem Lab Med. 2010 Dec;48(12):1713-8. Epub 2010 Aug 13.

Comparison of DNA extraction methods for multiplex polymerase chain reaction.

Viltrop T, Krjutskov K, Palta P, Metspalu A.

Anal Biochem. 2010 Mar 15;398(2):260-2. Epub 2009 Nov 20.

Evaluation of the 124-plex SNP typing microarray for forensic testing.

Krjutskov K, Viltrop T, Palta P, Metspalu E, Tamm E, Suvi S, Sak K, Merilo A, Sork H, Teek R, Nikopensius T, Kivisild T, Metspalu A.

Forensic Sci Int Genet. 2009 Dec;4(1):43-8. Epub 2009 May 15.

Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays.

Krjutskov K, Andreson R, Mägi R, Nikopensius T, Khrunin A, Mihailov E, Tammekivi V, Sork H, Remm M, Metspalu A.

Nucleic Acids Res. 2008 Jul;36(12):e75. Epub 2008 Jun 5.

Arrayed primer extension reaction for genotyping on oligonucleotide microarray.

Pullat J, Metspalu A.

Methods Mol Biol. 2008;444:161-7.

Robust SNP genotyping by multiplex PCR and arrayed primer extension.

Podder M, Ruan J, Tripp BW, Chu ZE, Tebbutt SJ.

BMC Med Genomics. 2008 Jan 31;1:5.

Genotyping of single nucleotide polymorphisms by arrayed primer extension.

Tebbutt SJ.

Methods Mol Biol. 2007;382:149-61.

An overview of current microarray-based human globin gene mutation detection methods.

Cremonesi L, Ferrari M, Giordano PC, Harteveld CL, Kleanthous M, Papasavva T, Patrinos GP, Traeger-Synodinos J.

Hemoglobin. 2007;31(3):289-311. Review.

Evaluation of arrayed primer extension for TP53 mutation detection in breast and ovarian carcinomas.

Kringen P, Bergamaschi A, Due EU, Wang Y, Tagliabue E, Nesland JM, Nehman A, Tönisson N, Børresen-Dale AL.

Biotechniques. 2005 Nov;39(5):755-61.

Arrayed primer extension resequencing of mutations in the TP53 tumor suppressor gene: comparison with denaturing HPLC and direct sequencing.

Le Calvez F, Ahman A, Tonisson N, Lambert J, Temam S, Brennan P, Zaridze DG, Metspalu A, Hainaut P.

Clin Chem. 2005 Jul;51(7):1284-7. No abstract available.

Evaluating the arrayed primer extension resequencing assay of TP53 tumor suppressor gene.

Tõnisson N, Zernant J, Kurg A, Pavel H, Slavin G, Roomere H, Meiel A, Hainaut P, Metspalu A.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5503-8.

Unravelling genetic data by arrayed primer extension.

Tõnisson N, Kurg A, Kaasik K, Lõhmussaar E, Metspalu A.

Clin Chem Lab Med. 2000 Feb;38(2):165-70.

Arrayed primer extension: solid-phase four-color DNA resequencing and mutation detection technology.

Kurg A, Tõnisson N, Georgiou I, Shumaker J, Tollett J, Metspalu A.

Genet Test. 2000;4(1):1-7.